• Class Number 3255
• Term Code 2930
• Class Info
• Unit Value 6 units
• Mode of Delivery In Person
• COURSE CONVENER
• Dr Alice Richardson
• LECTURER
• Dr Ben O'Neill
• Dr Grace Joshy
• Katie Glass
• Dr Wei Du
• Class Dates
• Class Start Date 25/02/2019
• Class End Date 31/05/2019
• Census Date 31/03/2019
• Last Date to Enrol 04/03/2019
SELT Survey Results

Biostatistics in Population Health (POPH8101)

This course will examine principles of biostatistics, in the context of real-world public health issues. The aim of the course is to help those without a technical background to read and interpret biostatistical content in the medical and public health literature.

Topics, chosen by frequency of occurrence in the literature, will include:

• Introduction to sampling distributions, hypothesis tests and estimation
• Analysis of normal data, including t-tests and linear regression
• Analysis of binary data, including 2x2 tables, Mantel-Haenszel methods and logistic regression
• Analysis of count data, including comparing rates between two groups,
• Poisson regression and survival analysis

Throughout the course, the emphasis will be on understanding the reasons why the techniques are appropriate, underlying assumptions and interpretation of results, rather than the mechanics of calculation. Each topic will draw upon one or two papers from the literature. Both lectures and computer laboratories will be used to facilitate learning and provide opportunities to explore specific topics in more detail.

## Learning Outcomes

Upon successful completion, students will have the knowledge and skills to:

By the end of the course, students will be able to:

• Explain the various mathematical and biostatistical concepts covered during the course
• Recognize differences in data distributions via visual displays
• Give examples of different types of data and know the appropriate techniques for analysing: continuous outcomes; binary data; count data; and survival data
• Interpret the results of: t-tests and linear regression; 2x2 tables, Mantel-Haenszel methods and logistic regression; Poisson regression; Cox regression; and meta-analysis
• Critically appraise the evidence presented in published research studies

## Research-Led Teaching

This course will use current research articles/projects to introduce students to interesting topics and problems in the field of biostatistics. All the lecturers of this course are senior academic researchers in the Research School of Population Health. In addition, all the tutors are active researchers/PhD scholars to engage students in learning activities and provide role models for students who want to undertake research in the future.

## Required Resources

• Betty R Kirkwood & Jonathan AC Sterne. Essential Medical Statistics (2e). Oxford: Blackwell Science Ltd, 2003.

‘Essential Medical Statistics’ is considered a classic among medical statisticians. An introductory textbook, it presents statistics with a clarity and logic that demystifies the subject, while providing a comprehensive coverage of advanced as well as basic methods. It is available for purchase from the Co-op Bookshop (Bldg #17 Union Court; Tel (02) 6249 6244). The Hancock Library (Bldg #43) also holds several copies for loan (RA407.K57 2003).

• Stata 15 I/C.

This course includes a hands-on introduction to the statistical analysis software Stata, the product of choice of most public health data analysts. You can use the software on computers in the Crawford Building (Bldg #132). It can also be purchased online through a company based in the ACT, http://www.surveydesign.com.au/. You can buy a licence for 12 months, or a perpetual licence.

If you find that there are sections that you are struggling with, try some supplementary reading of either of these books:

• Bland, M. An Introduction to Medical Statistics (3e). Oxford: Oxford University Press, 2000.
• Daniel WW. Biostatistics: A Foundation for Analysis in the Health Sciences (9e). New York: John Wiley & Sons, 2009.

If you are looking for an easy to read, non-mathematical introduction to medical statistics that concentrates on the concepts, and not the formulae, then try:

• Motulsky H. Intuitive Biostatistics (2e). New York: Oxford University Press, 2009.
• Swinscow TDV. Statistics at Square One (9e). London: BMJ Publishing Group, 1997.

If you want to delve deeper into the topic of biostatistics, try:

• Armitage P, Berry G & Matthews JNS. Statistical Methods in Medical Research (4e). Oxford: Wiley-Blackwell, 2008.

## Staff Feedback

Students will be given feedback in the following forms in this course:

• through verbal comments to individuals/focus groups;
• through written comments on assignments.

## Student Feedback

ANU is committed to the demonstration of educational excellence and regularly seeks feedback from students. Students are encouraged to offer feedback directly to their Course Convener or through their College and Course representatives (if applicable). The feedback given in these surveys is anonymous and provides the Colleges, University Education Committee and Academic Board with opportunities to recognise excellent teaching, and opportunities for improvement. The Surveys and Evaluation website provides more information on student surveys at ANU and reports on the feedback provided on ANU courses.

## Class Schedule

Week/Session Summary of Activities Assessment
1 Maths refresher
2 Variables and samples
3 Summarising and organising data
4 Sampling distributions and confidence intervals Assignment 1 released
5 Binary outcomes
6 Hypotheiss testing I Assignment 1 due; Quizzes 1 - 3 due
7 Hypothesis testing II
8 Power and sample size Assignment 2 released
9 Correlation and simple regression
10 Multiple regression Assignment 2 due
11 Logistic regression
12 Poisson regression Take-home exam released

## Assessment Summary

Assessment task Value Due Date Return of assessment Learning Outcomes
Online quizzes 1 - 3 6 % 07/04/2019 08/04/2019 1,2
Online quizzes 4 - 5 4 % 02/06/2019 03/06/2019 3,4
Assignment 1 20 % 07/04/2019 23/04/2019 1,2,3,5
Assignment 2 30 % 19/05/2019 03/06/2019 1,2,3,4,5
Take-home exam 40 % 09/06/2019 24/06/2019 1,2,3,4,5

* If the Due Date and Return of Assessment date are blank, see the Assessment Tab for specific Assessment Task details

## Policies

ANU has educational policies, procedures and guidelines, which are designed to ensure that staff and students are aware of the University’s academic standards, and implement them. Students are expected to have read the Academic Misconduct Rule before the commencement of their course. Other key policies and guidelines include:

## Assessment Requirements

The ANU is using Turnitin to enhance student citation and referencing techniques, and to assess assignment submissions as a component of the University's approach to managing Academic Integrity. For additional information regarding Turnitin please visit the ANU Online website. Students may choose not to submit assessment items through Turnitin. In this instance you will be required to submit, alongside the assessment item itself, hard copies of all references included in the assessment item.

## Moderation of Assessment

Marks that are allocated during Semester are to be considered provisional until formalised by the College examiners meeting at the end of each Semester. If appropriate, some moderation of marks might be applied prior to final results being released.

Value: 6 %
Due Date: 07/04/2019
Return of Assessment: 08/04/2019
Learning Outcomes: 1,2

Online quizzes 1 - 3

These three quizzes are designed to provide quick feedback on your understanding of topics as the semester progresses. You may attempt the quiz once only. Each quiz is worth 2% of your final grade.

Value: 4 %
Due Date: 02/06/2019
Return of Assessment: 03/06/2019
Learning Outcomes: 3,4

Online quizzes 4 - 5

These two quizzes are designed to provide quick feedback on your understanding of topics as the semester progresses. You may attempt the quiz once only. Each quiz is worth 2% of your final grade.

Value: 20 %
Due Date: 07/04/2019
Return of Assessment: 23/04/2019
Learning Outcomes: 1,2,3,5

Assignment 1

This topic-based assignment is designed to reinforce understanding of the material covered in lectures and tutorials.

The questions are based on production and interpretation of computer output, and the biostatistical content of a published paper; both the question sheet and the published paper will be available on WATTLE.

Value: 30 %
Due Date: 19/05/2019
Return of Assessment: 03/06/2019
Learning Outcomes: 1,2,3,4,5

Assignment 2

This topic-based assignment is designed to reinforce understanding of the material covered in lectures and tutorials.

The questions are based on production and interpretation of computer output, and the biostatistical content of a published paper; both the question sheet and the published paper will be available on WATTLE.

Value: 40 %
Due Date: 09/06/2019
Return of Assessment: 24/06/2019
Learning Outcomes: 1,2,3,4,5

Take-home exam

The take-home exam is designed to reinforce understanding of the material covered in lectures and tutorials, and to sythesise the material from across the semester.

The questions are based on production and interpretation of computer output, and the biostatistical content of a published paper; both the question sheet and the published paper will be available on WATTLE.

## Online Submission

You will be required to electronically sign a declaration as part of the submission of your assignment. Please keep a copy of the assignment for your records. Unless an exemption has been approved by the Associate Dean (Education) as submission must be through Turnitin.

## Hardcopy Submission

For some forms of assessment (hand written assignments, art works, laboratory notes, etc.) hard copy submission is appropriate when approved by the Associate Dean (Education). Hard copy submissions must utilise the Assignment Cover Sheet. Please keep a copy of tasks completed for your records.

## Late Submission

Late submission of assessment tasks without an extension are penalised at the rate of 5% of the possible marks available per working day or part thereof. Late submission of assessment tasks is not accepted after 10 working days after the due date, or on or after the date specified in the course outline for the return of the assessment item. Late submission is not accepted for take-home examinations.

## Referencing Requirements

Accepted academic practice for referencing sources that you use in presentations can be found via the links on the Wattle site, under the file named “ANU and College Policies, Program Information, Student Support Services and Assessment”. Alternatively, you can seek help through the Students Learning Development website.

## Returning Assignments

Assignments will be returned via Wattle.

## Extensions and Penalties

Extensions and late submission of assessment pieces are covered by the Student Assessment (Coursework) Policy and Procedure. The Course Convener may grant extensions for assessment pieces that are not examinations or take-home examinations. If you need an extension, you must request an extension in writing on or before the due date. If you have documented and appropriate medical evidence that demonstrates you were not able to request an extension on or before the due date, you may be able to request it after the due date.

## Resubmission of Assignments

Resubmission of assignments will be at the discretion of the course convenor in consulatation with the Associate Dean (Education).

## Privacy Notice

The ANU has made a number of third party, online, databases available for students to use. Use of each online database is conditional on student end users first agreeing to the database licensor’s terms of service and/or privacy policy. Students should read these carefully. In some cases student end users will be required to register an account with the database licensor and submit personal information, including their: first name; last name; ANU email address; and other information.
If any student chooses not to agree to the database licensor’s terms of service or privacy policy, the student will not be able to access and use the database. In these circumstances students should contact their lecturer to enquire about alternative arrangements that are available.

Academic Quality Assurance Committee monitors the performance of students, including attrition, further study and employment rates and grade distribution, and College reports on quality assurance processes for assessment activities, including alignment with national and international disciplinary and interdisciplinary standards, as well as qualification type learning outcomes.

Since first semester 1994, ANU uses a grading scale for all courses. This grading scale is used by all academic areas of the University.

## Support for students

The University offers students support through several different services. You may contact the services listed below directly or seek advice from your Course Convener, Student Administrators, or your College and Course representatives (if applicable).

## Convener

 Dr Alice Richardson 6125 0721 alice.richardson@anu.edu.au

### Research Interests

Multilevel modelling; Statistical properties of computer intensive methods; Multiple imputation of missing data; Statistics education

### Dr Alice Richardson

 Wednesday 09:30 10:30

## Instructor

 Dr Ben O'Neill 6125 5627 ben.oneill@anu.edu.au

## Instructor

 Dr Grace Joshy 50715 grace.joshy@anu.edu.au

## Instructor

 Katie Glass 52468 kathryn.glass@anu.edu.au

## Instructor

 Dr Wei Du 57492 wei.du@anu.edu.au