- Class Number 3354
- Term Code 3130
- Class Info
- Unit Value 6 units
- Mode of Delivery In Person
- EmPr Susan Howitt
- Dr Caitlin Byrt
- Dr Joseph Brock
- EmPr Susan Howitt
- Class Dates
- Class Start Date 22/02/2021
- Class End Date 28/05/2021
- Census Date 31/03/2021
- Last Date to Enrol 01/03/2021
Genetics underpins many contemporary social issues in health and agriculture. Modern biology has been transformed by DNA sequencing of full genomes and the application of recombinant DNA technology to a range of problems, including inherited disease, cancer biology and drug development, evolution of pandemics, development of better crops, antibiotic action for example. Applying and evaluating genetic technologies relies on an understanding of the principles of molecular genetics, which will be covered in this course.
This course introduces the molecular mechanisms involved in the storage and expression of genetic information in both prokaryotes and eukaryotes. Topics to be covered include: genome structure and evolution, DNA structure and packaging; DNA replication and repair; transcription; regulation of gene expression; RNA processing; protein synthesis and the genetic code. These processes will be illustrated with case studies, ranging from the human genome and genetic disease to genetically modified crops.
The course includes a lab project that reinforces lecture material and introduces students to key strategies and techniques of molecular genetics.
Note: Graduate students attend joint classes with undergraduates but are assessed separately.
Upon successful completion, students will have the knowledge and skills to:
- Explain the basic processes involved in the expression of genetic information (DNA replication; mutagenesis and DNA repair; mRNA transcription and processing; gene regulation; protein synthesis; genome structure and evolution)
- Apply knowledge of the roles and functions of these processes to a range of problems and examples
- Predict outcomes when these processes are perturbed by mutation (genetic disease) or the use of inhibitors and drugs
- Elucidate differences in gene organization between prokaryotes and eukaryotes
- Interpret and analyse experimental and theoretical problems involving these processes
- Apply knowledge and research applications for example, in designing experiments or analysing examples from the literature
- Communicate experimental results and conclusions in a scientific report
BIOL6161 encourages students to develop a critical attitude towards science and to understand its evidence-based nature. Students will have opportunities to discuss case studies, problems and questions in class and online. These will be based on topical issues and applications of the material covered. Contemporary and historical controversies in genetics will also be introduced. These activities aim to show students how science evolves, as well as the relevance of genetics. The practical component consists of a semester-long research project in which students isolate and analyse mutants, giving them an opportunity to experience experimental strategies in genetics and use fundamental techniques. This also provides experience in recording, handling and interpreting both quantitative and qualitative data obtained in the experiments. The emphasis in the practical project is on generating and evaluating data because students must use experimental evidence to support a conclusion about the genotypes of the mutants they have isolated.
The textbook is Genetics: A Conceptual Approach by Benjamin Pierce, 6th edition
Recommended student system requirements
ANU courses commonly use a number of online resources and activities including:
- video material, similar to YouTube, for lectures and other instruction
- two-way video conferencing for interactive learning
- email and other messaging tools for communication
- interactive web apps for formative and collaborative activities
- print and photo/scan for handwritten work
- home-based assessment.
To fully participate in ANU learning, students need:
- A computer or laptop. Mobile devices may work well but in some situations a computer/laptop may be more appropriate.
- Speakers and a microphone (e.g. headset)
- Reliable, stable internet connection. Broadband recommended. If using a mobile network or wi-fi then check performance is adequate.
- Suitable location with minimal interruptions and adequate privacy for classes and assessments.
- Printing, and photo/scanning equipment
For more information please see https://www.anu.edu.au/students/systems/recommended-student-system-requirements
Students will be given feedback in the following forms in this course:
- Written comments on lab reports
- Explanations of correct answers and common mistakes for tests
- Online multiple choice question bank
- Feedback to the whole class through in-lecture activities to test understanding and discussions of lab reports.
ANU is committed to the demonstration of educational excellence and regularly seeks feedback from students. Students are encouraged to offer feedback directly to their Course Convener or through their College and Course representatives (if applicable). The feedback given in these surveys is anonymous and provides the Colleges, University Education Committee and Academic Board with opportunities to recognise excellent teaching, and opportunities for improvement. The Surveys and Evaluation website provides more information on student surveys at ANU and reports on the feedback provided on ANU courses.
|Week/Session||Summary of Activities||Assessment|
|1||Module 1 DNA replication and repair; weeks 1-3||Test, pre-lab assignment and practical report|
|2||Module 2 Gene structure, expression and regulation in prokaryotes; weeks 4-6||Test, pre-lab assignment and short practical report|
|3||Module 3 Gene structure, expression and regulation in eukaryotes; weeks 7-9||Test|
|4||Module 4 Genomes and evolution; weeks 10-11||Test, pre-lab assignment and practical report|
|5||Module 5 Case studies and revision; weeks 11-12|
The class will be split into three groups for practical classes. All BIOL6161 students should select Group B. Information on how to select a group is available on Wattle.
|Assessment task||Value||Due Date||Return of assessment||Learning Outcomes|
|Laboratory reports||33 %||*||*||2,3,5,6,7|
|Lab quizzes||12 %||*||*||3,5,6,7|
|End of Semester Exam||30 %||03/06/2021||01/07/2021||1,2,3,4,5,6,7|
|PeerWise participation||5 %||*||*||1-5|
* If the Due Date and Return of Assessment date are blank, see the Assessment Tab for specific Assessment Task details
ANU has educational policies, procedures and guidelines, which are designed to ensure that staff and students are aware of the University’s academic standards, and implement them. Students are expected to have read the Academic Misconduct Rule before the commencement of their course. Other key policies and guidelines include:
The ANU is using Turnitin to enhance student citation and referencing techniques, and to assess assignment submissions as a component of the University's approach to managing Academic Integrity. For additional information regarding Turnitin please visit the Academic Integrity . In rare cases where online submission using Turnitin software is not technically possible; or where not using Turnitin software has been justified by the Course Convener and approved by the Associate Dean (Education) on the basis of the teaching model being employed; students shall submit assessment online via ‘Wattle’ outside of Turnitin, or failing that in hard copy, or through a combination of submission methods as approved by the Associate Dean (Education). The submission method is detailed below.
Moderation of Assessment
Marks that are allocated during Semester are to be considered provisional until formalised by the College examiners meeting at the end of each Semester. If appropriate, some moderation of marks might be applied prior to final results being released.
The final exam is worth 30% of your grade. It will cover the entire course and will include some questions that require integration of the material in different modules and the practical course. A pass in your aggregate mark for the final exam plus the four tests is required to pass the course overall.
Please note, that where a date range is used in the Assessment Summary in relation to exams, the due date and return date indicate the approximate timeframe in which the exam will be held and results returned to the student (official end of Semester results released on ISIS). Students should consult the course wattle site and the ANU final examination timetable to confirm the date, time and venue of the exam.
Assessment Task 1
Learning Outcomes: 2,3,5,6,7
You will write full reports for the first and third practical experiments, and a short report for the second, and these will be submitted through Turnitin. Guides, report sheets and marking rubrics are provided in the lab manual and on Wattle.
The due dates for the three lab reports are: 22nd March, 6th May and 17th May at 11.55 pm.
The practical component of the course is an integrated lab and online experience, covering theory, experimental design and data analysis as well as hands-on lab skills. Remote students will be provided with data for each experiment and will have additional data interpretation activities to complete to replace the on-campus experiment
Assessment Task 2
Learning Outcomes: 1,2,3,4
There will be 4 online tests worth 5% each, one covering each of the first 4 modules. Tests will be open for 30 hours from 6 pm Wednesday to midnight Thursday in weeks 4,6,9 and 11. Marks and feedback will be provided through Wattle one week after the test.
Assessment Task 3
Learning Outcomes: 3,5,6,7
There will be three lab quizzes worth 4% each. These will be associated with a self-paced tutorial that introduces students to the theory and experimental basis for the lab experiments.
These will be due on 8th March, 19th April and 10th May.
Assessment Task 4
Learning Outcomes: 1,2,3,4,5,6,7
End of Semester Exam
The date range in the Assessment Summary indicates the start of the end of semester exam period and the date official end of semester results are released on ISIS. Please check the ANU final Examination Timetable http://www.anu.edu.au/students/program-administration/assessments-exams/examination-timetable to confirm the date, time and location of the mid-semester exam.
Assessment Task 5
Learning Outcomes: 1-5
PeerWise is an online resource that enables students to write, answer and comment on multiple choice questions. Marks will be allocated according to the level of participation, with requirements for numbers of questions answered, comment on and written. Students are expected to contribute on an on-going basis throughout the semester. Further details are available on the Wattle site.
Academic integrity is a core part of the ANU culture as a community of scholars. At its heart, academic integrity is about behaving ethically, committing to honest and responsible scholarly practice and upholding these values with respect and fairness.
The ANU commits to assisting all members of our community to understand how to engage in academic work in ways that are consistent with, and actively support academic integrity. The ANU expects staff and students to be familiar with the academic integrity principle and Academic Misconduct Rule, uphold high standards of academic integrity and act ethically and honestly, to ensure the quality and value of the qualification that you will graduate with.
The Academic Misconduct Rule is in place to promote academic integrity and manage academic misconduct. Very minor breaches of the academic integrity principle may result in a reduction of marks of up to 10% of the total marks available for the assessment. The ANU offers a number of online and in person services to assist students with their assignments, examinations, and other learning activities. Visit the Academic Skills website for more information about academic integrity, your responsibilities and for assistance with your assignments, writing skills and study.
You will be required to electronically sign a declaration as part of the submission of your assignment. Please keep a copy of the assignment for your records. Unless an exemption has been approved by the Associate Dean (Education) submission must be through Turnitin.
For some forms of assessment (hand written assignments, art works, laboratory notes, etc.) hard copy submission is appropriate when approved by the Associate Dean (Education). Hard copy submissions must utilise the Assignment Cover Sheet. Please keep a copy of tasks completed for your records.
Late submission box
Noting the implications of Policy: Student assessment (coursework) Item 7
PLEASE SELECT EITHER:
No submission of assessment tasks without an extension after the due date will be permitted. If an assessment task is not submitted by the due date, a mark of 0 will be awarded.
Late submission of assessment tasks without an extension are penalised at the rate of 5% of the possible marks available per working day or part thereof. Late submission of assessment tasks is not accepted after 10 working days after the due date, or on or after the date specified in the course outline for the return of the assessment item. Late submission is not accepted for take-home examinations.
If both statements are valid and apply to different assignments, clarify which policy to which assignment.
Late submission of assessment tasks without an extension are penalised at the rate of 5% of the possible marks available per working day or part thereof. Late submission of assessment tasks is not accepted after 10 working days after the due date, or on or after the date specified in the course outline for the return of the assessment item.
Accepted academic practice for referencing sources that you use in presentations can be found via the links on the Wattle site, under the file named “ANU and College Policies, Program Information, Student Support Services and Assessment”. Alternatively, you can seek help through the Students Learning Development website.
Marks and feedback for each test will be provided online 1 week after the test closes.
Lab reports will be returned two weeks after submission.
PeerWise marks will be allocated two weeks after the final deadline.
Extensions and Penalties
Extensions and late submission of assessment pieces are covered by the Student Assessment (Coursework) Policy and Procedure. Extensions may be granted for assessment pieces that are not examinations or take-home examinations. If you need an extension, you must request an extension in writing on or before the due date. If you have documented and appropriate medical evidence that demonstrates you were not able to request an extension on or before the due date, you may be able to request it after the due date.
Distribution of grades policy
Academic Quality Assurance Committee monitors the performance of students, including attrition, further study and employment rates and grade distribution, and College reports on quality assurance processes for assessment activities, including alignment with national and international disciplinary and interdisciplinary standards, as well as qualification type learning outcomes.
Since first semester 1994, ANU uses a grading scale for all courses. This grading scale is used by all academic areas of the University.
Support for students
The University offers students support through several different services. You may contact the services listed below directly or seek advice from your Course Convener, Student Administrators, or your College and Course representatives (if applicable).
- ANU Health, safety & wellbeing for medical services, counselling, mental health and spiritual support
- ANU Diversity and inclusion for students with a disability or ongoing or chronic illness
- ANU Dean of Students for confidential, impartial advice and help to resolve problems between students and the academic or administrative areas of the University
- ANU Academic Skills and Learning Centre supports you make your own decisions about how you learn and manage your workload.
- ANU Counselling Centre promotes, supports and enhances mental health and wellbeing within the University student community.
- ANUSA supports and represents undergraduate and ANU College students
- PARSA supports and represents postgraduate and research students
Susan Howitt - education and student learning
EmPr Susan Howitt
Dr Caitlin Byrt
Dr Joseph Brock