- Code BIOL6243
- Unit Value 6 units
- Offered by Biology Teaching and Learning Centre
- ANU College ANU Joint Colleges of Science
- Course subject Biology
- Areas of interest Bioinformatics, Biology
In Sem 2 2022, this course is on campus with remote adjustments only for participants with unavoidable travel restrictions/visa delays.
This course provides an introduction to the key methods and technologies of bioinformatics as pertinent to genomics. These are the fastest growing fields of biology and perhaps science.
Bioinformatics is a rapidly growing scientific discipline at the interface of genomics, statistics and computer science that has distinct but overlapping aspects: the development of computational infrastructure (eg. algorithms, programs, databases) and their use to analyse a wide variety of biological data. Among these data, genes, transcripts and epigenetic features play a central role. Their rapid and large-scale acquisition in today's genomics, transcriptomics, proteomics and other -omics projects poses the major challenge of modern biology. The large-scale and genome-wide analysis of these data relies on advances in bioinformatics and statistics.
As computer literacy is central to bioinformatics, it is also central to this course. Accordingly, the course includes short sections on computer programming using the Python and R programming languages. We further cover advanced work practices employed during bioinformatics research, including code testing and use of version control systems. Research topics covered will include techniques for sequence comparison, population and comparative genomics, and transcript analysis.
Note: Graduate students attend joint classes with undergraduates but are assessed separately.
Upon successful completion, students will have the knowledge and skills to:
- Describe and apply a variety of sophisticated work practices in bioinformatics, including computer programming.
- Describe and evaluate current research procedures across a range of advanced topics in bioinformatics.
- Evaluate and interpret current literature in areas of bioinformatic practice.
- Design, implement and critically evaluate research methodology in the context of advanced bioinformatic analysis of DNA sequence data.
- Demonstrate the ability to construct and evaluate hypotheses about genomic data from mathematical and statistical models through analytical and computational methods.
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- Assignments on five topics (20% ea) distributed throughout the semester including computer programming exercise (100) [LO 1,2,3,4,5]
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The expected workload will consist of approximately 130 hours throughout the semester including:
- Face-to face component which may consist of 2 x 2 hour computer labs per week (total 48 hours).
- Approximately 82 hours of self directed study which will include preparation for computer labs and other assessment tasks.
Students are expected to actively participate and contribute towards discussions.
To be determined
Requisite and Incompatibility
The equivalent of BIOL2151 or BIOL3161, and some statistical knowledge (equivalent to BIOL2001 or BIOL2202 or STAT1003 or STAT1008). Some previous experience in computerr programming will be an advantage.
Tuition fees are for the academic year indicated at the top of the page.
Commonwealth Support (CSP) Students
If you have been offered a Commonwealth supported place, your fees are set by the Australian Government for each course. At ANU 1 EFTSL is 48 units (normally 8 x 6-unit courses). More information about your student contribution amount for each course at Fees.
- Student Contribution Band:
- Unit value:
- 6 units
If you are a domestic graduate coursework student with a Domestic Tuition Fee (DTF) place or international student you will be required to pay course tuition fees (see below). Course tuition fees are indexed annually. Further information for domestic and international students about tuition and other fees can be found at Fees.
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